Don't Waste Your Time Working up Bad Data Caused by Ion Suppression

High-performance liquid-chromatography is one of the most important and common quantitative and qualitative methods for measuring small biochemical molecules in metabolomics.  To ensure you have the ability to make accurate measurements make sure you monitor ion suppression.

Try our semi-targeted analysis workflow that automatically corrects for ion suppression, normalizes samples, and reports platform QC parameters.  It is so economical your data will thank you!

ion suppression

The Complete Reporting of All Peaks protocol (CRAP) is the most commonly used protocol in metabolomics today. Are you still producing CRAP data?

You know the majority of your peaks are artifacts?  Most of what remains are adducts or fragments, but they are all unknowns. 

You know your peaks are suppressed and too often unknowns.

Why not make your data worth working up?

PUT THE CRAP BEHIND YOU AND MOVE TO IROA-DRIVEN ACCURATE DATA.

TRUQUANT COMPLEX ISOTOPIC INTERNAL STANDARD AND CLUSTERFINDER SOFTWARE ENSURE DATA QUALITY

  • Semi-targeted. Provides quantitation and identification (with built-in libraries) for hundreds of IROA and non-IROA peaks in your sample
  • Automatically corrects for most variances, including instrumental, matrix effect and sample preparation
  • Sample-to-sample normalization
  • Corrects for all ion losses
  • Assures quality, reproducible data, built-in QC Platform monitoring
  • Economical – less than the cost of the plasticware used in preparing a sample

IROA Technologies

Once the most appropriate high-performance liquid chromatography method has been selected, a follow-up validation process should be performed to ensure the credibility of the HPLC analysis process.

IROA Technologies develops products to enable metabolomics and metabolomics measurements. We employ uniquely labeled internal standards that are easily identified in mass spectral data.  Our software algorithms seek out hundreds of peaks and automatically identifies compounds and their adducts or fragments, provides quantitation, and corrects for ion suppression. We are the developers of metabolic profiling technologies that facilitate the measurements of biological systems. 

Contact With Us

Send us your details and queries, and we will be happy to help you.
Contact Us Today!