WHAT is IROA?
Isotopic Ratio Outlier Analysis IROA is a simple and direct metabolic profiling technique which embeds unique signatures, specifically using 95% and 5% U-13C, into biochemical metabolites for relative quantitation by mass spectrometry (MS) and uses software algorithms to find, idenitify and quantitate these specific peaks. IROA can be applied to many life science applications (toxicology, diagnostics, drug development, bioprocess, etc.).
IROA utilizes both pre-labeled complex Internal Standards for targeted or untargeted metabolomics and kits for generating specific Internal Standards taylored to experimental cell types, including bacterial, yeast and mammalian cell lines.